Penile Injections (ICI) for Erectile Dysfunction (Trimix, Bimix, EDEX and Caverject): All You Need to Know – Erectile Dysfunction (ED) Care, Cialis Plus Edex.


Intracorporeal Injection Therapy (ICI) for Treatment of Erectile Dysfunction in NYC

Oral medications such as Viagra, Cialis and Stendra initially work for 80% of men. When oral medications such as Viagra, Cialis, Levitra, and Stendra do not work well or these medications are contraindicated, injections of medications in the penis often provides an effective treatment option for erectile dysfunction. Penile injections are performed using a very small needle and are nearly painless.

A few different medications are available to choose from that can be injected in the penis to produce a good direction.

Medications used for penile injections act on the blood vessels to improve blood flow to the penis. These medications include Prostaglandin E1 (PGE1), Trimix (which is a combination of PGE1, phentolamine, and papaverine). Add atropine to Trimix and you have QuadMix. PGE1 is also known as alprostadil. PGE1 can also be purchased in prepackaged form as Caverject or Edex.

Bimix is a combination of phentolamine and papaverine and associated with less risk of pain which is a side effect of PGE1 (alprostadil).

In general injectable medications are highly effective but they are associated with some side effects which do not occur with oral medications. The most common side effect of injectable medications is pain, which is more common with prostaglandin alone. When prostaglandin is used alone 30-40% of men report pain which occurs when the medication starts working typically 10-15 minutes after injection. With Trimix and Bimix the chances of pain are much lower. Pain typically goes away after a few hours.

Additional risks of injectable medications are priapism (erection that lasts more than 3-4 hours), risk of Peyronie’s disease secondary to trauma from injections (scar formation and curvature). Should an erection last more than 3-4 hours, the patient needs to go to the nearest emergency room for treatment.

Penile injection therapy is a well-tolerated treatment for ED with high effectiveness. It is appropriate for men do not achieve a desirable results with oral treatment options such as Viagra, Cialis, Levitra, and Stendra. Penile injections are also used as part of penile rehabilitation therapy after radical prostatectomy.

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We offer affordable, highest-quality urology care with or without insurance. Find out our office hours or directions to our office. We offer weekday, weekend and evening office hours.

Dr. Alex Shteynshlyuger is a board certified urologist, who specializes in all aspects of care for sexual problems in men including ED, premature ejaculation and other sexual concerns. He has successfully treated hundreds of men with sexual problems including ED and poor libido. We see patients from all parts of New York City (Manhattan, Brooklyn, Queens, Bronx, Staten Island), Long Island, Westchester and New Jersey as well as other parts in the USA, Canada, South America and the Caribbean and other international patients. We also offer emergency care for men with urological problems.

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