Cialis vs Flomax for BPH: What You Should Know
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
tamsulosin (Rx)
- abiraterone abiraterone increases levels of tamsulosin by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Avoid coadministration of abiraterone with substrates of CYP2D6. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate.
- amifostine amifostine, tamsulosin. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine.
- amiodarone amiodarone increases levels of tamsulosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Dose reduction may be neeed for coadministered drugs that are predominantly metabolized by CYP3A.
Minor (2)
- benazepril tamsulosin, benazepril. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. May increase risk of hypotension.
- captopril tamsulosin, captopril. Either increases effects of the other by pharmacodynamic synergism. Minor/Significance Unknown. May increase risk of hypotension.
- abametapir Serious – Use Alternative (1) abametapir increases levels of tamsulosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. For 2 weeks after abametapir application, avoid taking drugs that are CYP3A4 substrates. If not feasible, avoid use of abametapir.
- abiraterone Monitor Closely (1) abiraterone increases levels of tamsulosin by affecting hepatic enzyme CYP2D6 metabolism. Use Caution/Monitor. Avoid coadministration of abiraterone with substrates of CYP2D6. If alternative therapy cannot be used, exercise caution and consider a dose reduction of the CYP2D6 substrate.
- alfuzosin Serious – Use Alternative (1) alfuzosin, tamsulosin. Either increases effects of the other by additive vasodilation. Avoid or Use Alternate Drug. Risk of hypotension.
- amifostine Monitor Closely (1) amifostine, tamsulosin. Either increases effects of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Coadministration with blood pressure lowering agents may increase the risk and severity of hypotension associated with amifostine. When amifostine is used at chemotherapeutic doses, withhold blood pressure lowering medications for 24 hr prior to amifostine; if blood pressure lowering medication cannot be withheld, do not administer amifostine.
- amiodarone Monitor Closely (2) amiodarone increases levels of tamsulosin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Dose reduction may be neeed for coadministered drugs that are predominantly metabolized by CYP3A.
Adverse Effects
>10%
1-10%
Postmarketing Reports
Signs and symptoms of orthostasis, including syncope
Infrequent reports of dyspnea, palpitations, hypotension, atrial fibrillation, arrhythmia, and tachycardia
During cataract and glaucoma surgery, a variant of small pupil syndrome known as Intraoperative Floppy Iris Syndrome (IFIS) has been reported in association with alpha1 blocker therapy
Skin desquamation including reports of Stevens-Johnson syndrome, erythema multiforme, and dermatitis exfoliative
Allergic-type reactions (eg, skin rash, urticaria, pruritus, angioedema, respiratory symptoms) have been reported with positive rechallenge
Warnings
Contraindications
Cautions
Use with caution in coronary artery disease, liver disease, general anesthesia
Prostatic cancer should be ruled out before therapy is initiated
Discontinue if angina symptoms occur or worsen
Intraoperative floppy iris syndrome has been reported in patients receiving alpha1 blockers at time of cataract surgery; association is unclear
Patients with sulfa allergy have rarely developed allergic reaction; avoid use if previous sulfa allergy reactions have been life-threatening
Pregnancy & Lactation
Pregnancy
No data are available on use in pregnant women
No adverse developmental effects observed in animal studies administering tamsulosin to rats or rabbits during organogenesis
Infertility
- Males: Abnormal ejaculation including ejaculation failure, ejaculation disorder, retrograde ejaculation, and ejaculation decrease has been associated with therapy; studies in rats revealed significantly reduced fertility in males considered to be due to impairment of ejaculation, which was reversible
- Females: Drug is not indicated for use in women; female fertility in rats was significantly reduced, considered to be due to impairment of fertilization
Lactation
There are no data on presence of drug in human milk, effects on breastfed infant, or on milk production
No data are available; owing to potential of tamsulosin to cause hypotension, breastfeeding is not recommended if taking tamsulosin
Pregnancy Categories
A: Generally acceptable. Controlled studies in pregnant women show no evidence of fetal risk.
B: May be acceptable. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk.
C: Use with caution if benefits outweigh risks. Animal studies show risk and human studies not available or neither animal nor human studies done.
D: Use in LIFE-THREATENING emergencies when no safer drug available. Positive evidence of human fetal risk.
X: Do not use in pregnancy. Risks involved outweigh potential benefits. Safer alternatives exist.
Pharmacology
Mechanism of Action
Blocks alpha1a adrenergic receptor in smooth muscle of prostate, decreasing bladder neck and urethral resistance
Absorption
Peak plasma time: With food, 6-7 hr; fasting, 4-5 hr
Distribution
Metabolism
Metabolites: Glucuronide and sulfate conjugates (inactive)
Elimination
Administration
Oral Administration
Administer 30 minutes after same meal each day
Images
Patient Handout
USES: Tamsulosin is used by men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and the bladder. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night).Tamsulosin belongs to a class of drugs known as alpha blockers.Do not use this medication to treat high blood pressure.
HOW TO USE: Read the Patient Information Leaflet if available from your pharmacist before you start taking this medication and each time you get a refill. If you have any questions, ask your doctor or pharmacist.Take this medication by mouth as directed by your doctor, usually once daily, 30 minutes after the same meal each day. Swallow this medication whole. Do not crush, chew, or open the capsules.The dosage is based on your medical condition and response to treatment.Tamsulosin may cause a sudden drop in your blood pressure, which could lead to dizziness or fainting. This risk is higher when you first start taking this drug, after your doctor increases your dose, or if you restart treatment after you stop taking it. During these times, avoid situations where you may be injured if you faint.Take this medication regularly to get the most benefit from it. To help you remember, take it at the same time each day.If you have not taken this drug for several days, contact your doctor to see if you need to be restarted at a lower dose.It may take up to 4 weeks before your symptoms improve. Tell your doctor if your condition does not improve or if it worsens.
SIDE EFFECTS: Dizziness, lightheadedness, drowsiness, runny/stuffy nose, or ejaculation problems may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: fainting.Rarely, males may have a painful or prolonged erection lasting 4 or more hours. If this occurs, stop using this drug and get medical help right away, or permanent problems could occur.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
PRECAUTIONS: Before taking tamsulosin, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure, certain eye problems (cataracts, glaucoma).This drug may make you dizzy or drowsy. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).Before having surgery (including cataract/glaucoma eye surgery), tell your doctor or dentist if you are taking or have ever taken this medication, and about all the other products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially dizziness and low blood pressure when getting up from a sitting or lying position. These side effects can increase the risk of falling.During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding.
DRUG INTERACTIONS: Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.Some products that may interact with this drug include: other alpha blocker drugs (such as prazosin, terazosin).If you are also taking a drug to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), your blood pressure may get too low which can lead to dizziness or fainting. Your doctor may need to adjust your medications to minimize this risk.Other medications can affect the removal of tamsulosin from your body, which may affect how tamsulosin works. Examples include azole antifungals (such as itraconazole, ketoconazole), clarithromycin, cobicistat, HIV protease inhibitors (such as lopinavir), mifepristone, ribociclib, ritonavir, among others.
OVERDOSE: If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe dizziness, fainting.
NOTES: Do not share this medication with others.Laboratory and/or medical tests (such as prostate exams, blood pressure) should be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
MISSED DOSE: If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
STORAGE: Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.
Information last revised August 2022. Copyright(c) 2022 First Databank, Inc.
IMPORTANT: HOW TO USE THIS INFORMATION: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.
Cialis vs Flomax for BPH: What You Should Know
ED (erectile dysfunction) and BPH (benign prostatic hyperplasia) often co-exist. In almost every BPH patient, there is a strong connection between ED and lower urinary tract symptoms.
The older they get, the bigger the risk for benign prostatic hyperplasia. BPH and urinary problems prevalence is 36% in men aged 60 to 69 and 24% in 40 to 49-year-olds.
The prostate growth makes it difficult for the urinary system to function. This causes urinary retention, change in urine flow, inability to empty the bladder, and more.
Today, doctors are using different BPH medication and prostate medication to keep the urinary symptoms in check. One of the most popular choices is Flomax (Tamsulosin) and Cialis (Tadalafil).
If you want to know the details about each medication for prostatic hyperplasia, particularly these two, then you’ve come to the right place. We compared their impact so that you don’t have to.
What is Cialis?
With almost 2 million prescriptions back in 2018, countless American patients have opted for Tadalafil to treat erectile dysfunction. When combined with sexual stimulation, Cialis increases blood flow and helps maintain an erection.
This prescription medication is FDA approved for treating ED and a prostate condition together. This prostate medication is available in different strengths. That includes 5 mg, 2.5 mg, 10 mg, and 20 mg tablets. It is one of type 2, 5 alpha-reductase inhibitors that creates a potent effect.
Get Your FREE PSA Lowering Diet Plan!
Cialis and BPH – How Does It Work?
Cialis can mitigate the symptoms of an enlarged prostate. This was seen in patients affected with benign prostatic hyperplasia. The constant growth makes the prostate big enough to trigger urinary issues.
The medication relieves troubles with urine flow and stabilizes urination. It relaxes the smooth muscle of the bladder and prostate. The enlarged prostate can benefit from a treatment such as this. But, the drug can’t protect people from STDs.
It is only there to help with urinary retention and manage urinary symptoms so that those struggling with an overactive bladder can sleep at night.
When talking about prostatic hyperplasia or an enlarged prostate, it’s important to point out that BPH means benign. Therefore it’s not cancer. Nor is it associated with prostate cancer. Only the symptoms of benign prostatic hyperplasia are somewhat similar to cancer. So, the treatment of benign prostatic hyperplasia is focused on easing the urinary issues.
What is Flomax?
Tamsulosin is a highly used oral medicine to mitigate problems of an enlarged prostate. It can’t make the prostate smaller, but it can relax the prostate and bladder muscles.
This medicine is an alpha-blocker (like Terazosin) and a treatment option for prostatic hyperplasia, as well as bladder and urinary troubles. The urinary tract can benefit from a treatment such as this.
Flomax and BPH – How Does It Work?
The prostate gland originates with prostate tissues in the walls of the urethra. Both the prostate tissue and urethra have a role to play. The tissue separates the gland into lobules while the urethra provides adequate urination.
When the prostate gland is affected by prostate growth, then Tamsulosin can relax the prostate and bladder muscles, allowing the body to pee easily. This medication can ensure symptom relief if you have urinary troubles, like urinary retention, abnormal urine flow, and frequent urination.
A patient with high blood pressure can’t use Tamsulosin to keep the blood pressure stable. The drug is known to trigger a sudden drop in blood pressure. This can make a patient prone to fainting and dizziness. So, only a doctor can suggest the best form of treatment and dose when taking Tamsulosin.
Which Works Better?
Many people want to know which one is better when dealing with an enlarged prostate gland and prostate symptoms. Both can help with a BPH symptom and control the impact of prostate enlargement.
But, which one would make for a better prostate medication? According to 2019 reports, experts studied the efficiency of Tamsulosin and Tadalafil medication.
Managing Urinary Issues
In the Tamsulosin group, 18% of patients had mild urinary tract issues, and 82% had moderate urinary tract problems. While in the Tadalafil group 24% had mild urinary complications, and 76% had moderate urinary symptoms.
Based on the final results, Tamsulosin had better efficacy than Tadalafil. It can better manage lower urinary tract symptoms with prostatic hyperplasia.
Managing ED
Both Tamsulosin and Tadalafil can improve erectile function and ease urinary issues. Even patients who don’t respond to Tadalafil show improvements in managing lower urinary tract symptoms with Tamsulosin and the other way around.
Prostate Supplements
However, these prescription medications often have nasty side effects that some patients prefer to avoid. Therefore, people are also using prostate supplements because of possible complications of traditional BPH treatment, like retrograde ejaculation.
These supplements seem to control benign prostatic hyperplasia. Although they can’t replace conventional treatment for enlarged prostate, options like Rye-grass, Pygeum, saw palmetto, and Beta-sitosterol remains very popular. These substances can ease the urinary issues from enlarged prostate to some extent, allowing the prostate and bladder to work correctly.
The prostate gland and urethra can benefit from alternative treatment methods such as these. Plus, benign prostatic hyperplasia can lead to urinary tract infection. That’s why it is crucial to mitigate the symptoms of prostatic hyperplasia as soon as possible.
Before initiating any treatment, you need to see a urologist (bladder specialist). They can suggest the most viable form of treatment and keep prostatic hyperplasia in check. If the urinary complications result from an enlarged prostate, you will need to receive proper therapy, as well as lifestyle adjustments. Your doctor will recommend the best course of action for prostatic hyperplasia or any other disease.
Ben’s Natural Supplements For Prostate Health
Total Health
Our natural supplement, Ben’s Total Health contains ingredients clinically proven to reduce prostate size, manage BPH symptoms and help you restore optimal prostate health.
Clinical trials and meta-studies show the active ingredients in Total Health have a positive impact on prostate volume, improve lower urinary tract symptoms, and decrease the risk of acute urinary retention.
Prostate Healer
We formulated Prostate Healer to effectively combat BPH and prostatitis and provide symptomatic relief from urgency, frequency, and nocturia. It works on the prostate, kidney, and bladder simultaneously, coaxing cells gently to resume normal function. So, by this action, you’re fighting against prostatitis and BPH.
If you’re like many men that use the formula, you’ll see a reduction in the number of times you get up to go to the bathroom to urinate. Plus, you’ll see an improvement in the flow of your urine.
Prostate Power
Our dietary supplement, Prostate Power, contains ingredients clinically proven to shrink an enlarged prostate and slow the progress of BPH and prostate disease.
The key active ingredients in Prostate Power have been shown in numerous clinical trials and meta-studies to shrink prostate volume, improve urine flow and decrease the risk of acute urinary retention.
Why Choose Ben’s Natural Health Supplements?
At Ben’s Natural Health, our motto is to combine holistic healing with modern science. Ben’s Natural Health is the world’s first high-quality, all-natural, scientifically proven clinical supplement company.
Our supplements are effective, natural and 100% side effect free.
Moreover, at Ben’s Natural Health, we have four rules for all our supplements:
- We only use the highest quality ingredients
- We only use them if they have been proven to work in independent, peer-reviewed double-blind studies
- With all our supplements, we find a way to get every ingredient into a single bottle
- We always formulate them in clinically significant doses of the most bioavailable form
And, finally, all our supplements come with a 30-day money-back guarantee on any unopened bottles.
We pride ourselves on offering excellent customer service. We offer a free health consultation where you can ask questions and receive tailored advice from our expert health consultants.
Conclusion
Benign prostatic hyperplasia treatments have come a long way. After years of research on enlarged prostate, experts have created many medicines and treatments. One of the most prescribed prostate medication options is Cialis and Flomax.
Because of how many people have been using them for benign prostatic hypertrophy, there were a lot of questions popping up about how effective they can be. Especially whether Cialis or Flomax was more potent in treating benign prostatic hyperplasia.
But, it’s important to note that works for others may not work for you. So, if you are having trouble with what prostate medication to pick for prostatic hyperplasia, consult with a specialist first. They will check your health state and suggest the most practical option for prostatic hyperplasia management.
Tamsulosin
Tamsulosin is an alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction.
Tamsulosin is a selective alpha-1A and alpha-1B adrenoceptor antagonist that exerts its greatest effect in the prostate and bladder, where these receptors are most common. Label It is indicated for the treatment of signs and symptoms of benign prostatic hypertrophy. Label Antagonism of these receptors leads to relaxation of smooth muscle in the prostate and detrusor muscles in the bladder, allowing for better urinary flow. Label Other alpha-1 adrenoceptor antagonists developed in the 1980s were less selective and more likely to act on the smooth muscle of blood vessels, resulting in hypotension. 5
Tamsulosin was first approved by the FDA on April 15, 1997. 6
Type Small Molecule Groups Approved, Investigational Structure
Structure for Tamsulosin (DB00706)
Pharmacology
Tamsulosin is indicated for the treatment of signs and symptoms of benign prostatic hyperplasia. Label
Tamsulosin is also used off label for the treatment of ureteral stones, prostatitis, and female voiding dysfunction. 4,7
Improve clinical decision support with information on contraindications & blackbox warnings, population restrictions, harmful risks, & more.
Tamsulosin is an alpha adrenoceptor blocker with specificity for the alpha-1A and alpha-1D subtypes, which are more common in the prostate and submaxillary tissue. 1 The final subtype, alpha-1B, are most common in the aorta and spleen. 1 Tamsulosin binds to alpha-1A receptors 3.9-38 times more selectively than alpha-1B and 3-20 times more selectively than alpha-1D. 1 This selectivity allows for a significant effect on urinary flow with a reduced incidence of adverse reactions like orthostatic hypotension. 1
Tamsulosin is a blocker of alpha-1A and alpha-1D adrenoceptors. Label,1 About 70% of the alpha-1 adrenoceptors in the prostate are of the alpha-1A subtype. Label By blocking these adrenoceptors, smooth muscle in the prostate is relaxed and urinary flow is improved. Label The blocking of alpha-1D adrenoceptors relaxes the detrusor muscles of the bladder which prevents storage symptoms. 1 The specificity of tamsulosin focuses the effects to the target area while minimizing effects in other areas. Label
Oral tamsulosin is 90% absorbed in fasted patients. Label The area under the curve is 151-199ng/mL*hr for a 0.4mg oral dose and 440-557ng/mL*hr for a 0.8mg oral dose. Label The maximum plasma concentration is 3.1-5.3ng/mL for a 0.4mg oral dose and 2.5-3.6ng/mL for a 0.8mg oral dose. Label Taking tamsulosin with food increases the time to maximum concentration from 4-5 hours to 6-7 hours but increases bioavailability by 30% and maximum plasma concentration by 40-70%. Label
Tamsulosin is 94%-99% protein bound, mostly to alpha-1-acid glycoprotein. Label
Tamsulosin is mostly metabolized in the liver by cytochrome P450 (CYP) 3A4 and 2D6, with some metabolism by other CYPs. Label,1 CYP3A4 can deacetylate tamsulosin to the M-1 metabolite or perform oxidative deamination to the AM-1 metabolite. 2,3 CYP2D6 can hydroxylate tamsulosin to the M-3 metabolite or demethylate tamsulosin to the M-4 metabolite. 2 Finally, an unknown enzyme can hydroxylate tamsulosin at a different position to form the M-2 metabolite. 2 The M-1, M-2, M-3, and M-4 metabolites can be glucuronidated or the M-1 and M-3 metabolites can undergo sulfate conjugation to form other metabolites before excretion. 3
Hover over products below to view reaction partners
97% of an orally administered does is recovered in studies, which 76% in the urine and 21% in the feces after 168 hours. Label 8.7% of the dose is excreted as unmetabolized tamsulosin. Label,1
The half life in fasted patients is 14.9±3.9 hours. Label The elimination half life is 5-7 hours and the apparent half life is 9 to 13 hours in healthy subjects. Label In patients who require tamsulosin, the apparent half life is 14-15 hours. Label
With structured adverse effects data, including: blackbox warnings, adverse reactions, warning & precautions, & incidence rates.
In the event of overdose, patients may experience hypotension and should lie down in a supine position to maintain blood pressure and heart rate. Label If further measures are required intravenous fluids should be considered. Label If further progression is required, vasopressors may be used and renal function should be monitored. Label Dialysis is unlikely to assist in treating overdose because tamsulosin is extensively protein bound. Label
Tamsulosin is not indicated for use in women and no studies have been performed in pregnancy, though animal studies have not shown fetal harm. Label Tamsulosin is excreted in the milk of rats but there is no available data on what the effect of this tamsulosin exposure may be. Label Animal studies have shown male and female rat fertility is affected by tamsulosin due to impairment of ejaculation and fertilization. Label In men, tamsulosin is associated with abnormal ejaculation. Label Tamsulosin is not mutagenic but may be carcinogenic at levels above the maximum recommended human dose. Label Female rats experience a slight increase in the rates of mammary gland fibroadenomas and adenocarcinomas. Label
Pathways Not Available Pharmacogenomic Effects/ADRs
Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
Our datasets provide approved product information including: dosage, form, labeller, route of administration, and marketing period.
International/Other Brands Betamsal (Hemofarm) / Contiflo XL (Ranbaxy) / Flomaxtra (Astellas) / Harnal D (Astellas) / Maxrin (Square) / Mecir (Boehringer Ingelheim) / Omexel (Astellas) / Omipro (Jelfa) / Omix (Astellas) / Omnic (Astellas Pharma Europe) / Pradif (Boehringer Ingelheim) / Ranomax (Ranbaxy) / Salover (Aversi) / Secotex (Boehringer Ingelheim) / Stronazon (Actavis) / Tamsact (Actavis) / Tamsol (Apex) / Tamsul (Aspen Pharmacare) / Urimax (Celeris) Brand Name Prescription Products
| Name | Dosage | Strength | Route | Labeller | Marketing Start | Marketing End | Region | Image |
|---|---|---|---|---|---|---|---|---|
| Flomax | Capsule | 0.4 mg/1 | Oral | Lake Erie Medical Dba Quality Care Produts Llc | 2010-05-13 | 2014-09-10 | US | |
| Flomax | Capsule | 0.4 mg/1 | Oral | bryant ranch prepack | 1997-09-12 | Not applicable | US | |
| Flomax | Capsule | 0.4 mg/1 | Oral | A S Medication Solutions | 1999-06-03 | Not applicable | US | |
| Flomax | Capsule | 0.4 mg/1 | Oral | RedPharm Drug, Inc. | 2019-04-16 | Not applicable | US | |
| Flomax | Capsule | 0.4 mg/1 | Oral | Boehringer Ingelheim Pharmaceuticals, Inc. | 1997-09-12 | 2021-11-30 | US | |
| Flomax | Capsule | 0.4 mg/1 | Oral | Cardinal Health | 1997-09-12 | 2012-09-30 | US | |
| Flomax | Capsule | 0.4 mg/1 | Oral | Physicians Total Care, Inc. | 2001-08-28 | Not applicable | US | |
| Flomax | Capsule, extended release | 0.4 mg | Oral | Boehringer Ingelheim (Canada) Ltd Ltee | 1998-06-19 | 2009-08-27 | Canada | |
| Flomax | Capsule | 0.4 mg/1 | Oral | REMEDYREPACK INC. | 2017-09-13 | 2020-04-06 | US | |
| Flomax | Capsule | 0.4 mg/1 | Oral | Boehringer Ingelheim Pharmaceuticals, Inc. | 1997-09-12 | 2014-11-03 | US |
Generic Prescription Products
| Name | Dosage | Strength | Route | Labeller | Marketing Start | Marketing End | Region | Image |
|---|---|---|---|---|---|---|---|---|
| Apo-tamsulosin CR | Tablet, extended release | 0.4 mg | Oral | Apotex Corporation | 2012-02-09 | Not applicable | Canada | |
| Ava-tamsulosin CR | Tablet, extended release | 0.4 mg | Oral | Avanstra Inc | 2011-09-19 | 2014-08-21 | Canada | |
| Jamp Tamsulosin | Capsule, extended release | 0.4 mg | Oral | Jamp Pharma Corporation | 2010-06-16 | Not applicable | Canada | |
| Mylan-tamsulosin | Capsule, extended release | 0.4 mg | Oral | Mylan Pharmaceuticals | 2007-08-16 | 2017-01-09 | Canada | |
| Ran-tamsulosin | Capsule, extended release | 0.4 mg | Oral | Ranbaxy Inc. | 2007-08-15 | 2012-06-13 | Canada | |
| Ratio-tamsulosin | Capsule, extended release | 0.4 mg / cap | Oral | TEVA Canada Limited | 2007-04-27 | 2021-07-30 | Canada | |
| Sandoz Tamsulosin | Capsule, extended release | 0.4 mg | Oral | Sandoz Canada Incorporated | 2007-05-16 | 2017-05-24 | Canada | |
| Sandoz Tamsulosin | Capsule, extended release | 0.4 mg | Oral | Sandoz Canada Incorporated | 2014-03-19 | Not applicable | Canada | |
| Sandoz Tamsulosin CR | Tablet, extended release | 0.4 mg | Oral | Sandoz Canada Incorporated | 2011-01-04 | Not applicable | Canada | |
| Tamsulosin Hydrochloride | Capsule | 0.4 mg/1 | Oral | Rebel Distributors | 2010-04-27 | Not applicable | US |
Mixture Products
| Name | Ingredients | Dosage | Route | Labeller | Marketing Start | Marketing End | Region | Image |
|---|---|---|---|---|---|---|---|---|
| Aglandin comp. 0,5 mg/0,4 mg-Hartkapseln | Tamsulosin hydrochloride (0.4 mg) + Dutasteride (0.5 mg) | Capsule | Oral | G.L. Pharma Gmb H | 2019-01-16 | Not applicable | Austria | |
| DUODART | Tamsulosin (0.4 MG) + Dutasteride (0.5 MG) | Capsule | Oral | บริษัท แกล็กโซสมิทไคล์น (ประเทศไทย) จำกัด | 2018-09-24 | Not applicable | Thailand | |
| DUODART 0,5 MG/0,4 MG KAPSÜL,30 KAPSÜL | Tamsulosin hydrochloride (0.4 mg) + Dutasteride (0.5 mg) | Capsule | Oral | GLAXOSMİTHKLİNE İLAÇLARI SAN. VE TİC. A.Ş. | 2020-08-14 | 2020-05-22 | Turkey | |
| DUODART 0,5 MG/0,4 MG KAPSÜL,7 KAPSÜL | Tamsulosin hydrochloride (0.4 mg) + Dutasteride (0.5 mg) | Capsule | Oral | GLAXOSMİTHKLİNE İLAÇLARI SAN. VE TİC. A.Ş. | 2020-08-14 | 2020-05-22 | Turkey | |
| DUODART 0,5 MG/0,4 MG KAPSÜL,90 KAPSÜL | Tamsulosin hydrochloride (0.4 mg) + Dutasteride (0.5 mg) | Capsule | Oral | GLAXOSMİTHKLİNE İLAÇLARI SAN. VE TİC. A.Ş. | 2020-08-14 | 2020-05-22 | Turkey | |
| Duodart Capsules 0.5mg/0.4mg | Tamsulosin (0.4 mg) + Dutasteride (0.5 mg) | Capsule | Oral | GLAXOSMITHKLINE PTE LTD | 2012-07-02 | Not applicable | Singapore | |
| Dutaglandin comp. 0,5 mg/0,4 mg-Hartkapseln | Tamsulosin hydrochloride (0.4 mg) + Dutasteride (0.5 mg) | Capsule | Oral | G.L. Pharma Gmb H | 2018-08-22 | Not applicable | Austria | |
| DuTamsul 0,5 mg/0,4 mg Hartkapseln | Tamsulosin hydrochloride (0.4 mg) + Dutasteride (0.5 mg) | Capsule | Oral | Genericon Pharma Gmb H | 2018-08-22 | Not applicable | Austria | |
| Dutasteride and Tamsulosin Hydrochloride | Tamsulosin hydrochloride (0.4 mg/1) + Dutasteride (0.5 mg/1) | Capsule | Oral | Prasco Laboratories | 2016-07-01 | 2021-01-31 | US | |
| Dutasteride and Tamsulosin Hydrochloride | Tamsulosin hydrochloride (0.4 mg/1) + Dutasteride (0.5 mg/1) | Capsule | Oral | Par Pharmaceutical, Inc. | 2015-11-18 | Not applicable | US |
Categories
- G04CA — Alpha-adrenoreceptor antagonists
- G04C — DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
- G04 — UROLOGICALS
- G — GENITO URINARY SYSTEM AND SEX HORMONES
- G04CA — Alpha-adrenoreceptor antagonists
- G04C — DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
- G04 — UROLOGICALS
- G — GENITO URINARY SYSTEM AND SEX HORMONES
- G01AE — Sulfonamides
- G01A — ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
- G01 — GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
- G — GENITO URINARY SYSTEM AND SEX HORMONES
- G04CA — Alpha-adrenoreceptor antagonists
- G04C — DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
- G04 — UROLOGICALS
- G — GENITO URINARY SYSTEM AND SEX HORMONES
- G04CA — Alpha-adrenoreceptor antagonists
- G04C — DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY
- G04 — UROLOGICALS
- G — GENITO URINARY SYSTEM AND SEX HORMONES
- Adrenergic Agents
- Adrenergic alpha-1 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Amides
- Cytochrome P-450 CYP2D6 Substrates
- Cytochrome P-450 CYP3A Substrates
- Cytochrome P-450 CYP3A4 Substrates
- Cytochrome P-450 Substrates
- Drugs that are Mainly Renally Excreted
- Drugs Used in Benign Prostatic Hypertrophy
- Genito Urinary System and Sex Hormones
- Genitourinary Agents
- Gynecological Antiinfectives and Antiseptics
- Hypotensive Agents
- Neurotransmitter Agents
- Peripheral alpha-1 blockers
- Selective Alfa-1-adrenergic Blocking Agents
- Sulfonamides
- Sulfones
- Sulfur Compounds
- Urological Agents
- Urologicals
show 4 more Substituents Alkyl aryl ether / Amine / Aminosulfonyl compound / Amphetamine or derivatives / Anisole / Aralkylamine / Aromatic homomonocyclic compound / Benzenesulfonamide / Benzenesulfonyl group / Ether / Hydrocarbon derivative / Methoxybenzene / Organic nitrogen compound / Organic oxide / Organic oxygen compound / Organic sulfonic acid or derivatives / Organonitrogen compound / Organooxygen compound / Organopnictogen compound / Organosulfonic acid amide / Organosulfonic acid or derivatives / Organosulfur compound / Phenol ether / Phenoxy compound / Phenylpropane / Secondary aliphatic amine / Secondary amine / Sulfonyl
Chemical Identifiers
References
Hun Wang, Jun Park, Min Kwon, Ji Shim, Bong Lee, Hong Jeon, “Controlled release formulation of tamsulosin hydrochloride and preparation process thereof.” U.S. Patent US20050100606, issued May 12, 2005.
- Dunn CJ, Matheson A, Faulds DM: Tamsulosin: a review of its pharmacology and therapeutic efficacy in the management of lower urinary tract symptoms. Drugs Aging. 2002;19(2):135-61. [Article]
- Matsushima H, Kamimura H, Soeishi Y, Watanabe T, Higuchi S, Tsunoo M: Pharmacokinetics and plasma protein binding of tamsulosin hydrochloride in rats, dogs, and humans. Drug Metab Dispos. 1998 Mar;26(3):240-5. [Article]
- Soeishi Y, Matsushima H, Watanabe T, Higuchi S, Cornelissen K, Ward J: Absorption, metabolism and excretion of tamsulosin hydrochloride in man. Xenobiotica. 1996 Jun;26(6):637-45. [Article]
- Rivard R: Tamsulosin: ureteral stones (distal). Hosp Pharm. 2015 Jan;50(1):31-3. doi: 10.1310/hjp5001-031. [Article]
- Lepor H, Roehrborn C: Historical Overview of Medical Therapy for Benign Prostatic Hyperplasia Reviews in Urology. [Article]
- FDA Approved Drug Products: Flomax [Link]
- Urology Times: Urologists no longer primary initiator of tamsulosin [Link]
Clinical Trials
| Phase | Status | Purpose | Conditions | Count |
|---|---|---|---|---|
| 4 | Active Not Recruiting | Treatment | Benign Prostatic Hyperplasia (BPH) / Lower Urinary Tract Symptoms (LUTS) | 1 |
| 4 | Active Not Recruiting | Treatment | Benign Prostatic Hyperplasia (BPH) / Overactive Bladder Syndrome (OABS) | 1 |
| 4 | Active Not Recruiting | Treatment | Lower Ureteric Stones | 1 |
| 4 | Completed | Basic Science | Benign Prostatic Hyperplasia (BPH) | 1 |
| 4 | Completed | Prevention | Postoperative Urinary Retention (POUR) | 2 |
| 4 | Completed | Treatment | Benign Prostatic Hyperplasia (BPH) | 4 |
| 4 | Completed | Treatment | Benign Prostatic Hyperplasia (BPH) / Benign Prostatic Hypertrophy / Overactive Bladder Syndrome (OABS) | 1 |
| 4 | Completed | Treatment | Benign Prostatic Hyperplasia (BPH) / Choroid Disease / Pupil Anomaly | 1 |
| 4 | Completed | Treatment | Benign Prostatic Hyperplasia (BPH) / Ischemic Heart Disease / Lower Urinary Tract Symptoms (LUTS) | 1 |
| 4 | Completed | Treatment | Benign Prostatic Hyperplasia (BPH) / Lower Urinary Tract Symptoms (LUTS) / Overactive Bladder Syndrome (OABS) | 1 |
Pharmacoeconomics
- Boehringer ingelheim pharmaceuticals inc
- Impax laboratories inc
- Mylan pharmaceuticals inc
- Sandoz inc
- Sun pharmaceutical industries ltd
- Synthon pharmaceuticals inc
- Teva pharmaceuticals usa
- Wockhardt ltd
- Zydus pharmaceuticals usa inc
- Actavis Group
- AQ Pharmaceuticals Inc.
- A-S Medication Solutions LLC
- Astellas Pharma Inc.
- Atlantic Biologicals Corporation
- Boehringer Ingelheim Ltd.
- Bryant Ranch Prepack
- Cadila Healthcare Ltd.
- Cardinal Health
- Diversified Healthcare Services Inc.
- GlaxoSmithKline Inc.
- Global Pharmaceuticals
- Kaiser Foundation Hospital
- Major Pharmaceuticals
- Mylan
- Pharmacy Service Center
- Physicians Total Care Inc.
- Preferred Pharmaceuticals Inc.
- Prepackage Specialists
- Prepak Systems Inc.
- Redpharm Drug
- Resource Optimization and Innovation LLC
- Sandoz
- Stat Rx Usa
- Synthon Pharmaceuticals Inc.
- Teva Pharmaceutical Industries Ltd.
- UDL Laboratories
- Vangard Labs Inc.
- Wockhardt Ltd.
- Zydus Pharmaceuticals
Dosage Forms
| Form | Route | Strength |
|---|---|---|
| Capsule | Oral | |
| Capsule, coated | Oral | 0.22 mg |
| Capsule, extended release | Oral | 0.4 mg |
| Capsule | Oral | 0.5 mg |
| Capsule | Oral | 0.4 mg/1 |
| Tablet | ||
| Tablet, soluble | Oral | |
| Tablet | 0.2 mg | |
| Tablet, film coated | Oral | 0.4 mg |
| Tablet, film coated | Oral | |
| Capsule | Oral | |
| Capsule, extended release | Oral | |
| Capsule, delayed release | Oral | |
| Capsule | Oral | 0.4 MG |
| Capsule, extended release | Oral | 0.4 mg / cap |
| Tablet, film coated, extended release | Oral | 0.4 mg |
| Capsule, delayed release pellets | Oral | |
| Capsule, coated | Oral | |
| Capsule, delayed release | Oral | 0.4 mg |
| Capsule, extended release | Oral | |
| Tablet, extended release | Oral | |
| Capsule | Oral | .4 mg/1 |
| Capsule | Oral | 0.4 mg/0.4mg |
| Tablet, film coated, extended release | Oral | 0.40 mg |
| Capsule, extended release | Oral | 400 MICROGRAMMI |
| Capsule | Oral | 0.4 MG |
| Tablet, extended release | Oral | 0.4 mg |
| Capsule, gelatin coated | ||
| Tablet, delayed release | Oral | |
| Tablet | Oral |
Prices
| Unit description | Cost | Unit |
|---|---|---|
| Flomax 0.4 mg capsule | 4.71USD | capsule |
| Tamsulosin hcl 0.4 mg capsule | 4.3USD | capsule |
| Flomax Cr 0.4 mg Extended-Release Tablet | 0.63USD | tablet |
| Mylan-Tamsulosin 0.4 mg Sustained-Release Capsule | 0.63USD | capsule |
| Novo-Tamsulosin 0.4 mg Sustained-Release Capsule | 0.57USD | capsule |
| Ran-Tamsulosin 0.4 mg Sustained-Release Capsule | 0.57USD | capsule |
| Ratio-Tamsulosin 0.4 mg Sustained-Release Capsule | 0.57USD | capsule |
| Sandoz Tamsulosin 0.4 mg Sustained-Release Capsule | 0.57USD | capsule |
| Tamsulosin 0.4 mg Sustained-Release Capsule | 0.57USD | capsule |
DrugBank does not sell nor buy drugs. Pricing information is supplied for informational purposes only.
Patents
| Patent Number | Pediatric Extension | Approved | Expires (estimated) | Region |
|---|---|---|---|---|
| US4703063 | No | 1987-10-27 | 2010-04-27 | US |
| CA2490299 | No | 2008-08-26 | 2023-12-24 | Canada |
| CA2144077 | No | 2005-05-24 | 2013-09-10 | Canada |
| US5565467 | No | 1996-10-15 | 2015-11-20 | US |
Properties
State Solid Experimental Properties
| Property | Value | Source |
|---|---|---|
| melting point (°C) | 230 | FDA Label |
| water solubility | Sparingly soluble in water | FDA Label |
Predicted Properties
| Property | Value | Source |
|---|---|---|
| Water Solubility | 0.00655 mg/mL | ALOGPS |
| logP | 3.05 | ALOGPS |
| logP | 2.04 | Chemaxon |
| logS | -4.8 | ALOGPS |
| pKa (Strongest Acidic) | 9.93 | Chemaxon |
| pKa (Strongest Basic) | 9.28 | Chemaxon |
| Physiological Charge | 1 | Chemaxon |
| Hydrogen Acceptor Count | 6 | Chemaxon |
| Hydrogen Donor Count | 2 | Chemaxon |
| Polar Surface Area | 99.88 Å 2 | Chemaxon |
| Rotatable Bond Count | 11 | Chemaxon |
| Refractivity | 108.86 m 3 ·mol -1 | Chemaxon |
| Polarizability | 43.95 Å 3 | Chemaxon |
| Number of Rings | 2 | Chemaxon |
| Bioavailability | 1 | Chemaxon |
| Rule of Five | Yes | Chemaxon |
| Ghose Filter | Yes | Chemaxon |
| Veber’s Rule | No | Chemaxon |
| MDDR-like Rule | No | Chemaxon |
Predicted ADMET Features
| Property | Value | Probability |
|---|---|---|
| Human Intestinal Absorption | + | 0.997 |
| Blood Brain Barrier | + | 0.5915 |
| Caco-2 permeable | – | 0.6473 |
| P-glycoprotein substrate | Substrate | 0.5911 |
| P-glycoprotein inhibitor I | Non-inhibitor | 0.5734 |
| P-glycoprotein inhibitor II | Non-inhibitor | 0.5522 |
| Renal organic cation transporter | Non-inhibitor | 0.8178 |
| CYP450 2C9 substrate | Non-substrate | 0.7898 |
| CYP450 2D6 substrate | Substrate | 0.8919 |
| CYP450 3A4 substrate | Substrate | 0.6012 |
| CYP450 1A2 substrate | Non-inhibitor | 0.7876 |
| CYP450 2C9 inhibitor | Inhibitor | 0.5916 |
| CYP450 2D6 inhibitor | Non-inhibitor | 0.8614 |
| CYP450 2C19 inhibitor | Non-inhibitor | 0.5056 |
| CYP450 3A4 inhibitor | Inhibitor | 0.718 |
| CYP450 inhibitory promiscuity | Low CYP Inhibitory Promiscuity | 0.6146 |
| Ames test | Non AMES toxic | 0.6245 |
| Carcinogenicity | Non-carcinogens | 0.6419 |
| Biodegradation | Not ready biodegradable | 1.0 |
| Rat acute toxicity | 2.4091 LD50, mol/kg | Not applicable |
| hERG inhibition (predictor I) | Weak inhibitor | 0.8367 |
| hERG inhibition (predictor II) | Non-inhibitor | 0.6971 |
ADMET data is predicted using admetSAR, a free tool for evaluating chemical ADMET properties. (23092397)
Spectra
Mass Spec (NIST) Not Available Spectra
| Spectrum | Spectrum Type | Splash Key |
|---|---|---|
| Predicted GC-MS Spectrum – GC-MS | Predicted GC-MS | Not Available |
| Predicted MS/MS Spectrum – 10V, Positive (Annotated) | Predicted LC-MS/MS | Not Available |
| Predicted MS/MS Spectrum – 20V, Positive (Annotated) | Predicted LC-MS/MS | Not Available |
| Predicted MS/MS Spectrum – 40V, Positive (Annotated) | Predicted LC-MS/MS | Not Available |
| Predicted MS/MS Spectrum – 10V, Negative (Annotated) | Predicted LC-MS/MS | Not Available |
| Predicted MS/MS Spectrum – 20V, Negative (Annotated) | Predicted LC-MS/MS | Not Available |
| Predicted MS/MS Spectrum – 40V, Negative (Annotated) | Predicted LC-MS/MS | Not Available |
Cialis and Prostate Health
This could be why it alleviates urinary symptoms associated with BPH. Cialis was approved for BPH after studies found that men who took 5 milligrams per day had improvements in both BPH and ED symptoms. The majority of side effects from Cialis are mild. [1]
Is Acid Reflux A side effect of Cialis? Possible side effects of Cialis include flushing, aside from a prolonged erection which is an emergency. Cialis may also cause headache, nasal congestion, heartburn, back pain, and muscle pain.
You can take Cialis and Flomax together.
The purpose of this study was to see if taking tadalafil (Cialis) and tamsulosin (Flomax) together would improve both urinary symptoms and erectile dysfunction. This combination of treatments was both safe and effective in reducing urinary symptoms and improving erectile function. [2]
Is Vidalista the same as Cialis? Tadalafil comes in many different forms, one of which is Generic Vidalista 40. Centurion Laboratories, an Indian company, produces it. Tadalafil is the main active element in the drug. It is used for ED or erectile dysfunction and lasts up to 36 hours.
How does Cialis affect urine?
Cialis is the first ED drug to be approved for treating benign prostatic hyperplasia (BPH). Commonly known as enlarged prostate, symptoms include difficulty starting to urinate, a weak urine stream, sudden urge to urinate, and frequent urination at night. [3]
Does alcohol stop Cialis from working? You could have problems if you take Cialis and drink too much. If you drink alcohol while taking Cialis, it can lower your blood pressure, which can be dangerous. If you experience headache, dizziness or fainting, you could fall and suffer fractures or other injuries.
Cialis is used to treat what?
In ED, Cialis acts by increasing the levels of a chemical called cyclic guanosine monophosphate (cGMP). This chemical helps increase blood flow to the penis. The chemical also relaxes muscle cells in the bladder, which helps to relieve urinary difficulties. This is likely to be why it eases the urinary symptoms of BPH.
Will Cialis make you bigger? This is false. Cialis cannot enlarge a man’s penis. However, the medication does increase blood flow to the area. Cialis may cause penises that don’t fully erect to appear larger.
What is the effect of Cialis on prostate size?
Cialis has been approved by the FDA as a treatment for enlarged prostate on September 6th, 2011. This medication may be prescribed to treat men who have both an enlarged prostate and erectile dysfunction (ED). Cialis is the first ED drug that has been approved for treating benign prostatic hyperplasia (BPH).
| Does Cialis reduce prostate size? | Does Cialis Work for BPH? |
| Does Cialis help reduce prostate size? | Can Cialis shrink the prostate? |
Can you take Cialis recreationally? You may be putting your health at risk if you use prescription oral erectile dysfunction medications without a medical need. For example, you could end up with counterfeit drugs.
Can Cialis help reduce the size of an enlarged prostate?
The FDA has approved Cialis for the treatment of enlarged prostate on Oct. 6, 2011. It can also be used to treat men who have both an enlarged prostate and erectile dysfunction (ED). Cialis is the first ED drug that has been approved for treating benign prostatic hyperplasia (BPH). [4]
How long does it take for Cialis to work for BPH?
60% to 70% of men enjoyed clinical improvement in LUTS after treatment with tadalafil. Approximately half reported improvement after 1 week of treatment. Approximately 70% reported improvement by 4 weeks.
How long does it take cialis 5mg to work for treating BPH?
Approximately 60% to 70% of men who took tadalafil for treatment of lower urinary tract symptoms reported clinical improvement. Approximately half of the men reported improvement after one week of treatment, and approximately 70% reported improvement after four weeks of treatment.
How long does it take for Cialis to work for BPH?
In randomized clinical trials, sildenafil, vardenafil, and tadalafil have all been shown to reduce lower urinary tract symptoms in men with BPH. Several studies enrolled over 1,000 men in trials that were brief, lasting 8 to 12 weeks. Both men with moderate and severe lower urinary tract symptoms improved. [5]
What are the benefits of Flomax and Cialis for treating BPH?
Cialis is a good option for men with both benign prostatic hyperplasia and erectile dysfunction. Flomax is most commonly used to treat symptoms of benign prostatic hyperplasia (BPH). Both of these drugs can cause a drop in blood pressure. They wouldn’t be a good choice for you if you already have low blood pressure or if your blood pressure varies. [6]
